Characterization of Inductively Coupled Plasma Time-of-Flight Mass Spectrometry in Combination with Collision/Reaction Cell Technology–Insights from Highly Time-Resolved Measurements Burger, M.,… Read More »
Multi-Element Analysis of Single Nanoparticles
Nanoparticles have unique physicochemical properties compared to their bulk analogs. They are increasingly incorporated into industrial processes and consumer products, including use as additives, drug delivery agents, and catalysts, to name just a few. Advances in nanomaterials have enabled exciting technological and scientific capabilities. However, the safety of nanoparticles still a topic of debate. Reliable analytical techniques and methods are required to gain greater understanding of the behavior of nanoparticles and their potential risks.
Single particle inductively coupled plasma mass spectrometry (sp- ICP-MS) is already employed as a tool for the rapid analysis of size and number concentration of inorganic nanoparticles at low environmentally relevant concentrations (ng/kg-µg/kg). The icpTOF extends the capabilities of traditional sp-ICP-MS to include multi-element analysis of single nanoparticles, which is critical for characterization of complex systems. The icpTOF is uniquely suited for the detection and quantitative characterization of nanoparticles in unknown or poorly characterized samples. It has, for example, been successfully applied for the identification of engineered nanoparticles in the high background of natural particles based on elemental fingerprinting of individual particles.
Single-Particle Mass Spectrometry of Titanium and Niobium Carbonitride Precipitates in Steels This contribution demonstrates how multi-element single particle (me-sp) analysis… Read More »
Application of ICP-TOFMS for Real-Time Measurement of Trace Elements in Automotive Exhaust Particulate Matters from Engine Oil Additives Hagino, Hiroyuki… Read More »
Experiments of in vivo HgSe nanoparticle formation demonstrate the potential of multi-element single particle icpTOF analysis for complex biological samples. Olga… Read More »
Multi-Element Analysis of Single Nanoparticles by ICP-MS using Quadrupole and Time-of Flight Technologies Naasz Steffi, et al. Journal of Analytical… Read More »
Analysis of Inorganic Nanoparticles by Single-Particle Inductively Coupled Plasma Time-of-Flight Mass Spectrometry Hendriks, Lyndsey, et al. CHIMIA International Journal for… Read More »
Where is the Nano? Analytical Approaches for the Detection and Quantification of TiO2 Engineered Nanoparticles in Surface Waters Gondikas, Andreas et… Read More »
Olga Borovinskaya, Steffi Boehme TOFWERK, RIKILT, The Netherlands Single particle inductively coupled plasma mass spectrometry (sp-ICP- MS) has established itself… Read More »
Antonia Praetorius, Alexander Gundlach-Graham, Eli Goldberg, Willi Fabienke, Jana Navratilova, Andreas Gondikas, Ralf Kaegi, Detlef Günther, Thilo Hofmann and Frank… Read More »
Single particle (SP) ICP-MS is routinely applied for quantitative determination of size and number concentration of metal-containing nanoparticles at low,… Read More »