Antonia Praetorius, Alexander Gundlach-Graham, Eli Goldberg, Willi Fabienke, Jana Navratilova, Andreas Gondikas, Ralf Kaegi, Detlef Günther, Thilo Hofmann and Frank… Read More »
Multi-Element Analysis of Single Nanoparticles
Nanoparticles have unique physicochemical properties compared to their bulk analogs. They are increasingly incorporated into industrial processes and consumer products, including use as additives, drug delivery agents, and catalysts, to name just a few. Advances in nanomaterials have enabled exciting technological and scientific capabilities. However, the safety of nanoparticles still a topic of debate. Reliable analytical techniques and methods are required to gain greater understanding of the behavior of nanoparticles and their potential risks.
Single particle inductively coupled plasma mass spectrometry (sp- ICP-MS) is already employed as a tool for the rapid analysis of size and number concentration of inorganic nanoparticles at low environmentally relevant concentrations (ng/kg-µg/kg). The icpTOF extends the capabilities of traditional sp-ICP-MS to include multi-element analysis of single nanoparticles, which is critical for characterization of complex systems. The icpTOF is uniquely suited for the detection and quantitative characterization of nanoparticles in unknown or poorly characterized samples. It has, for example, been successfully applied for the identification of engineered nanoparticles in the high background of natural particles based on elemental fingerprinting of individual particles.
Single particle (SP) ICP-MS is routinely applied for quantitative determination of size and number concentration of metal-containing nanoparticles at low,… Read More »
Fe and Fe oxide nanoparticles (NPs) are used for water and soil remediation, drug delivery, medical treatment and imaging, as… Read More »
There is a growing interest in quantitative analysis of nanoparticles (NPs) in complex environmental and biological media. Single particle-(sp)-ICP-MS provides an… Read More »
Olga Borovinskaya1, Sabrina Gschwind2, Bodo Hattendorf2, Martin Tanner1, Detlef Guenther2 1TOFWERK AG, Thun Switzerland, 2ETH, Zurich, Switzerland This paper describes… Read More »