Kiesilä, A., et al. Angewandte Chemie, 2017. DOI: 10.1002/anie.201704054 The formation of complexes between hexafluorophosphate (PF6−) and tetraisobutyloctahydroxypyridinearene has been thoroughly… Read More »
Structural Characterization of Supramolecular Complexes
Supramolecular chemistry has developed into a very active and sophisticated field during the last decades, as recognized by the Nobel Prize awarded to Cram, Lehn and Pedersen. It focuses on highly complex self-assembled structures with applications in materials technology, catalysis, medicine and electronics. Structural characterization of the complexes still represents a major challenge; yet, it is crucial to know the geometry of these compounds to understand their physico-chemical properties. Classically, structural characterization is carried out by cumbersome X-ray crystallography or NMR.
TOFWERK’s IMS-TOF is an attractive alternative to these techniques as it is fast, requires only minute samples amounts and allows calculation of collision cross sections directly from ion mobility drift times consistent with the crystal structures and the hydrodynamic diameters.