VOCs in Human Breath

Fast, Sensitive Analysis of Human Breath Emissions of VOCs

Fast real-time measurements
Ultra-low limits of detection in seconds
High mass resolving power for accurate identification

Humidity independent measurements allow reliable quantification
Dedicated breath inlet with disposable mouthpieces

Background

VOCs in Human Breath

Breath analysis is a growing field in medical research and drug testing. Human breath contains hundreds of VOCs, many at trace concentration levels. Characterization of compounds in human breath can be used for non-invasive diagnosis of diseases, assessment of physiological functions, therapy control, and pharmacokinetic studies. Analysis demands ultra-low detection limits, broad dynamic range, and fast time response. With unmatched sensitivity and mass resolving power, the Vocus CI-TOF is a cutting-edge solution for online analysis of VOCs in breath.

Solutions

Real-Time Detection of VOCs in Breath Using the Vocus CI-TOF
- High mass resolving power enabling accurate identification and quantification in breath
- Highest sensitivity available with sub-ppt LOD and independent of humidity
- Fast time response allows real-time VOC quantification during air inhalation and exhalation.
- Optional automated reagent ion switching between an expanded suite of reagent ions for expanding chemical scope and specificity
View Breath Inlet Product Sheet
Real-time monitoring of VOCs in human breath throughout the consumption of a Ricola^TM herb cough drop. Human breath was directly sampled into the inlet of a Vocus 2R PTR before and after ingestion of the cough drop. Concentrations of the monitored species spanned more than 6 orders of magnitude during the experiment (ppt to ppm).