In this poster from ASMS 2015, we show that the IMS-TOF can separate different types of isomers across all lipid classes.
The Tofwerk IMS-TOF provides unsurpassed separation capabilities for isomeric lipids. Due to the distinct biochemical properties of different isomers, the characterization of isomers is currently one of the hottest topics in lipidomic research. For example, isomers of phosphatidylinositol phosphates (PIPs) that differ in the position of the phosphate group can either be involved in protein trafficking to cell membranes (PI3P) or be essential for correct functioning of the Golgi apparatus (PI4P).
