This poster from ASMS 2016 (San Antonio, TX) demonstrates\u00a0a new method for sensitive detection and quantification of size and element composition of\u00a0Fe-rich nanoparticles<\/p>\n
Fe and Fe oxide nanoparticles (NPs) are used for water and soil remediation, drug delivery, medical treatment and imaging, as well as for surface coating and catalysis applications. \u00a0Monitoring the release of manufactured iron- containing nanomaterials into the environment is of special interest since iron is an ubiquitously occurring element with importance to living organisms and ecosystem.<\/span><\/p>\n Single particle ICP-MS (sp-ICP-MS) is more and more being used to measure number concentrations, mass and size of NPs due to its low detection limits and quantification capabilities.\u00a0Fe is a challenging element for detection using ICP-MS due to 56ArO+ plasma gas ions interfering on the most abundant 56Fe isotope, resulting in high detection limits. Moreover, Fe is one of the abundant elements in the earth crust and is present in high concentrations in dissolved form<\/p>\n The TOFWERK icpTOF offers simultaneous multielement\u00a0single particle detection. This can be used to\u00a0trace engineered NPs in the high background of\u00a0natural particles and to study chemical transformation\u00a0of NPs. The instrument is equipped with a Q-cell\u00a0technology, which can suppress ArO+ interferences\u00a0and improve the LOD for Fe. Its temporal resolution of\u00a030 \u03bcs minimizes the contribution of dissolved Fe to the\u00a0particle signal.<\/p>\n <\/p>","protected":false},"excerpt":{"rendered":"