VOCs in Human Breath
Fast, Sensitive Analysis of Human Breath Emissions of VOCs
- Fast real-time measurements
- Ultra-low limits of detection in seconds
- High mass resolving power for accurate identification
- Humidity independent measurements allow reliable quantification
- Dedicated breath inlet with disposable mouthpieces
Background
VOCs in Human Breath
Breath analysis is a growing field in medical research and drug testing. Human breath contains hundreds of VOCs, many at trace concentration levels. Characterization of compounds in human breath can be used for non-invasive diagnosis of diseases, assessment of physiological functions, therapy control, and pharmacokinetic studies. Analysis demands ultra-low detection limits, broad dynamic range, and fast time response. With unmatched sensitivity and mass resolving power, the Vocus CI-TOF is a cutting-edge solution for online analysis of VOCs in breath.
Solutions
Real-Time Detection of VOCs in Breath Using the Vocus CI-TOF
- High mass resolving power enabling accurate identification and quantification in breath
- Highest sensitivity available with sub-ppt LOD and independent of humidity
- Fast time response allows real-time VOC quantification during air inhalation and exhalation.
- Optional automated reagent ion switching between an expanded suite of reagent ions for expanding chemical scope and specificity
Real-time monitoring of VOCs in human breath throughout the consumption of a RicolaTM herb cough drop. Human breath was directly sampled into the inlet of a Vocus 2R PTR before and after ingestion of the cough drop. Concentrations of the monitored species spanned more than 6 orders of magnitude during the experiment (ppt to ppm).
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