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3D Tissue Compositional Profiling with the icpTOF: Analytical Chemistry Publication and EWCPS 2017 Poster

Three-Dimensional Reconstruction of the Tissue-Specific Multi-Elemental Distribution within Ceriodaphnia dubia via Multimodal Registration Using Laser Ablation ICP-Mass Spectrometry and X-Ray Spectroscopic Techniques

Stijn J. M. Van Malderen, Brecht Laforce, Thibaut Van Acker, Charlotte Nys, Maarten De Rijcke, Riet De Rycke, Michiel De Bruyne, Matthieu Boone, Karel A.C. De Schamphelaere, Olga Borovinskaya, Björn De Samber, Laszlo Vincze, and Frank Vanhaecke. 

Conference poster presented at European Winter Conference on Plasma Spectrochemistry; 2017 Feb 20-24; Sankt Anton am Arlberg, Austria.

Analytical Chemistry, 2017. DOI: 10.1021/acs.analchem.7b00111

In a recent publication in Analytical Chemistry and a poster presented at EWCPS 2017, researchers from Ghent University demonstrate a combined approach for 3D compositional profiling of a small water flea. Using the icpTOF equipped with a high-throughput rapid laser ablation system, they imaged a total of 59 thin sections at 5 µm lateral resolution in less than 30 h. The 3D image was reconstructed from the large data set of 2D maps using a data fusion approach and μ-CT data. Using the complete, all-element mass spectra recorded by the icpTOF, they introduced a multi-isotope extraction approach in order to improve the signal-to-noise ratios.




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